Benadryl

Benadryl Allergy Ultratab (Diphenhydramine 25mg)

Benadryl·$12.99
Generic Worth ItSave 31%
70% confidence371 votes
Verified Apr 2026

Generic Alternative

Kirkland Signature

Kirkland Signature Allergy Medicine (Diphenhydramine 25mg)

Kirkland Signature

Costco

$8.99

260

Same Quality

74

Close Enough

37

Not Worth It

Quick Facts

Ingredients ComparedConfirmed

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70%

Same Quality

20%

Close Enough

10%

Not Worth It

Evidence (1)

Ingredients✓ Confirmedby adminApr 6, 2026

Kirkland Signature Allergy Medicine contains diphenhydramine 25mg, identical to Benadryl Allergy. Diphenhydramine is an off-patent drug; FDA-approved generics are required to be bioequivalent. Manufactured by Perrigo. One of the best-known examples of overpaying for a name brand.

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